TXA for Mastectomy

The Breast Surgery Research Group of the Department of Surgery at McMaster University’s Faculty of Health Sciences has received funding from the BRIGHT Run to investigate a way to reduce the incidence of seroma and hematoma among patients who...

Young Women with Breast Cancer

Young women with breast cancer have a number of unique unmet needs e.g. premature treatment-induced menopause, infertility, strain in relationships and decisions regarding contralateral mastectomy. Young women with breast cancer will be interviewed. This study will help inform us...

Antineoplastic activity of Vitamin D

Both vitamin D and melatonin have the potential to affect the growth of cancer cells. However, high quality evidence in humans is lacking. In this randomized trial women who have recently been diagnosed with breast cancer will receive both...

Cardiac Biomarker Study

Doxorubicin and trastuzumab are effective drugs for treating breast cancer, but they can cause damage to the heart muscle. A study is being conducted to evaluate whether blood tests called cardiac biomarkers (troponins and pro-brain natiuretic peptides) which...

Novel Molecular Breast Imaging Camera

In this study a new type of imaging camera which depends on a radioactive probe that detects cancer was evaluated in women at high risk of developing breast cancer (e.g. BRCA1/2 carriers). The goal was to detect early breast...

Thyroid hormone receptors

Thyroid hormone receptors in breast cancer: prognosis, predictive and therapeutic implications. Researchers: Dr. B Dhesy The survival of breast cancer patients has improved in the past 20 years due to advancements in anti-hormonal and anti-HER2 directed therapies. These therapies...

Innovation in Breast Cancer Treatment

Innovation in breast cancer treatment isn’t always dramatic. For Carla Purcell of Brantford, the best possible treatment for her breast cancer included radiation therapy. To do that, she needed to know when to breathe in and hold it. But...

Identifying tumour margin

Development of an intra-surgical decision support system for use by breast cancer surgeons to identify tumour margin Researchers: Dr. M. Farquharson Breast Cancer is the second leading cause of cancer death among women. There is a need to optimize...

CD200 in Human Breast Cancer

It has been recognized that an established tumor is able to shut down immune rejection cells so they cannot work. A molecule called CD200 appears to be very important in this shut down process. In this project, breast cancer...

Phase II study

Vasomotor symptoms (hot flashes are a troublesome symptom in women with breast cancer. The use of hormones is contraindicated. In this randomized trial a non-needle treatment using acupuncture-like transcutaneous electrical stimulation (ALTENS) is being studied to see if...